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Ivermectin study #75 of 86
3/11 Meta
Bryant et al., Research Square, doi:10.21203/rs.3.rs-317485/v1 (OSF preprints 3/11) (Preprint)
Ivermectin for prevention and treatment of COVID-19 infection: a systematic review and meta-analysis
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Systematic review and meta analysis of 21 RCTs finding mortality RR 0.32 [0.14-0.72], and prophylaxis case RR 0.14 [0.09-0.21].

Bryant et al., 3/11/2021, preprint, 7 authors.
risk of death, 68.0% lower, RR 0.32, p = 0.006.
risk of COVID-19 case, 86.0% lower, RR 0.14, p < 0.001.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.
Details of all 86 studies    Meta analysis
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