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0 0.5 1 1.5 2+ Mortality 85% primary Improvement Relative Risk c19ivermectin.com Carvallo et al. Ivermectin for COVID-19 EARLY Favors ivermectin Favors control
Carvallo, 46 patient ivermectin early treatment study: 85% lower mortality [p=0.08] https://c19p.org/carvallo
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Safety and Efficacy of the Combined Use of Ivermectin, Dexamethasone, Enoxaparin and Aspirina against COVID-19 the I.D.E.A. Protocol
Carvallo et al., Journal of Clinical Trials, 11:459 (preprint 9/15/20)
15 Sep 2020    Source   PDF   Share   Tweet
Prospective trial of ivermectin, dexamethasone, enoxaparin, and aspirin, showing no hospitalization for mild cases, and lower mortality for moderate/severe patients.
risk of death, 85.4% lower, RR 0.15, p = 0.08, treatment 1 of 32 (3.1%), control 3 of 14 (21.4%), NNT 5.5, moderate/severe patients, the only treatment death was a patient already in the ICU before treatment, primary outcome.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
This study is excluded in the after exclusion results of meta analysis: minimal details of groups provided.
Carvallo et al., 9/15/2020, prospective, Argentina, South America, peer-reviewed, mean age 55.7, 3 authors, dosage 36mg days 1, 8, dose varied depending on patient condition - mild 24mg, moderate 36mg, severe 48mg, this trial uses multiple treatments in the treatment arm (combined with dexamethasone, enoxaparin, and aspirin) - results of individual treatments may vary.
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