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0 0.5 1 1.5 2+ Case 96% Improvement Relative Risk c19ivermectin.com Carvallo et al. Ivermectin for COVID-19 Prophylaxis Favors ivermectin Favors control
Carvallo, 229 patient ivermectin prophylaxis study: 96% fewer cases [p<0.0001] https://c19p.org/carvalloprep2
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Usefulness of Topic Ivermectin and Carrageenan to Prevent Contagion of Covid 19 (IVERCAR)
Carvallo et al., NCT04425850 (Preprint)
19 Oct 2020    Source   PDF   Share   Tweet
Prophylaxis study using ivermectin and carrageenan showing 0 of 131 cases from treated healthcare workers, compared to 11 of 98 control.
The effect is likely to be primarily due to ivermectin - the author has later reported that carrageenan is not necessary [youtube.com].
risk of case, 96.3% lower, RR 0.04, p < 0.001, treatment 0 of 131 (0.0%), control 11 of 98 (11.2%), NNT 8.9, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm).
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
This study is excluded in the after exclusion results of meta analysis: concern about potential data issues.
Carvallo et al., 10/19/2020, prospective, Argentina, South America, preprint, 1 author, dosage 1mg days 1-14, this trial uses multiple treatments in the treatment arm (combined with iota-carrageenan) - results of individual treatments may vary.
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