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All Studies   Meta Analysis   Recent: 
Safety, Tolerability, and Pharmacokinetics of Escalating High Doses of Ivermectin in Healthy Adult Subjects
Guzzo et al., J. Clinical Pharmacology, doi:10.1177/009127002237994
1/1/2013    Source   PDF   Share   Tweet
Safety study concluding that ivermectin was generally well tolerated, with no indication of associated CNS toxicity for doses up to 10 times the highest FDA-approved dose. Adverse effects were similar between ivermectin and placebo and did not increase with dose. Authors also show that the plasma concentration is much higher when taken with food (geometric mean AUC 2.6 times higher).
Guzzo et al., 1/1/2013, peer-reviewed, 9 authors.
All Studies   Meta Analysis
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