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0 0.5 1 1.5 2+ Mortality 75% Improvement Relative Risk c19ivermectin.com Hill et al. Ivermectin for COVID-19 META ANALYSIS Favors ivermectin Favors control
Hill, ivermectin meta analysis: 75% lower mortality [p=0.0002] https://c19p.org/hill
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Meta-analysis of randomized trials of ivermectin to treat SARS-CoV-2 infection
Hill et al., Research Square, doi:10.21203/rs.3.rs-148845/v1 (Preprint) (meta analysis)
19 Jan 2021    Source   PDF   Share   Tweet
Meta analysis of 18 ivermectin RCTs with 2,282 patients showing faster viral clearance (dose and duration dependent), improved clinical recovery, and lower hospitalization and mortality. In six RCTs of moderate or severe infection, there was a 75% reduction in mortality, RR 0.25 [0.12-0.52], p = 0.0002.
A documentary about the external influences changing the conclusions of this study, and the resulting negative impacts, can be found at [drtesslawrie.substack.com].
A sponsor reportedly required the conclusion of this paper to be changed against the wishes of the authors (to suggest that more trials should be done as opposed to the existing evidence being sufficient) [francesoir.fr, reddit.com, youtube.com]. Reportedly, Unitaid had influence over the conclusions [trialsitenews.com, worldcouncilforhealth.org]. See also [roundingtheearth.substack.com].
Note that one of the 18 studies in this analysis has since been withdrawn (Elgazzar).
Currently there are 82 ivermectin for COVID-19 studies, showing 53% [39‑64%] lower mortality, 31% [11‑46%] lower ventilation, 54% [36‑67%] lower ICU admission, 38% [24‑49%] lower hospitalization, and 78% [67‑86%] lower cases.
risk of death, 75.0% lower, RR 0.25, p < 0.001.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Hill et al., 1/19/2021, preprint, 40 authors.
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