Ivermectin treatment may improve the prognosis of patients with COVID-19

Ivermectin study #17 of 113 Meta Analysis

9/24 Late treatment study

Khan et al., Archivos de Bronconeumología, doi:10.1016/j.arbres.2020.08.007 (Letter)
Ivermectin treatment may improve the prognosis of patients with COVID-19

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Retrospective 115 ivermectin patients and 133 control patients showing significantly lower death and faster viral clearance.

Some potential issues and the authors' response can be found in [1, 2].

Khan et al., 9/24/2020, retrospective, Bangladesh, South Asia, preprint, median age 35.0, 8 authors, dosage 12mg single dose.

risk of death, 87.0% lower, RR 0.13, p < 0.05, treatment 1 of 115 (0.9%), control 9 of 133 (6.8%).

risk of ICU admission, 89.5% lower, RR 0.11, p = 0.007, treatment 1 of 115 (0.9%), control 11 of 133 (8.3%).

time to viral-, 73.3% lower, relative time 0.27, p < 0.001, treatment 115, control 133.

Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.

[1] sciencedirect.com/science/article/pii/S0300289620305214

[2] sciencedirect.com/science/article/pii/S0300289620305548

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Please send us corrections, updates, or comments. Vaccines and treatments are both extremely valuable and complementary. All practical, effective, and safe means should be used. Elimination of COVID-19 is a race against viral evolution. No treatment, vaccine, or intervention is 100% available and effective for all current and future variants. Denying the efficacy of any method increases the risk of COVID-19 becoming endemic; and increases mortality, morbidity, and collateral damage. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. Treatment protocols for physicians are available from the FLCCC.

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