News report on the use of ivermectin in La Pampa, Argentina, showing lower mortality with treatment.
La Pampa et al., 8/10/2021, retrospective, Argentina, South America, preprint, 1 author, dosage 600μg/kg days 1-5.
risk of death, 27.4% lower, RR 0.73, treatment 3269, control 18149.
risk of combined death/ICU, 38.0% lower, RR 0.62, treatment 3269, control 18149.
risk of death, 33.4% lower, RR 0.67, treatment 3269, control 18149, >40yo.
risk of death, 44.0% lower, RR 0.56, treatment 3269, control 18149, >40yo including comorbidities.
This study is excluded in meta analysis: detail too minimal.
Effect extraction follows
pre-specified rules
prioritizing more serious outcomes. For an individual study the most serious
outcome may have a smaller number of events and lower statistical signficance,
however this provides the strongest evidence for the most serious outcomes
when combining the results of many trials.