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0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Mortality 70% Improvement Relative Risk Severe case 55% c19ivermectin.com/loue.html Favors ivermectin Favors control
17 April 2021 - Early treatment study
Ivermectin and COVID-19 in Care Home: Case Report
Loue et al., J. Infectious Diseases and Epidemiology, doi:10.23937/2474-3658/1510202 (Peer Reviewed)
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Small quasi-randomized (patient choice) study with 25 PCR+ patients in a nursing home offered ivermectin, of which 10 chose to be treated. The mean age was 83.5 in the treatment group and 81.8 in the control group. There was lower mortality and fewer serious cases with treatment.
risk of death, 70.0% lower, RR 0.30, p = 0.34, treatment 1 of 10 (10.0%), control 5 of 15 (33.3%), NNT 4.3.
risk of severe case, 55.0% lower, RR 0.45, p = 0.11, treatment 3 of 10 (30.0%), control 10 of 15 (66.7%), NNT 2.7.
Effect extraction follows pre-specified rules prioritizing more serious outcomes.
Loue et al., 4/17/2021, retrospective quasi-randomized (patient choice), France, Europe, peer-reviewed, 2 authors, dosage 200μg/kg single dose.
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