1/20 In Vitro
et al., Communications Biology, doi:10.1038/s42003-020-01577-x (Peer Reviewed) (In Vitro)
Identification of 3-chymotrypsin like protease (3CLPro) inhibitors as potential anti-SARS-CoV-2 agents
Identification of 3-chymotrypsin like protease (3CLPro) inhibitors as potential anti-SARS-CoV-2 agents
Computational molecular modeling screening and in vitro analysis for inhibitory effects on SARS-CoV-2 specific 3CLpro enzyme, showing that ivermectin blocked more than 85% of 3CLpro activity of SARS-CoV-2. Antiviral activity of ivermectin mediated through the blocking of α/β1 importin has been previously established, this analysis suggests an additional antiviral mechanism of ivermectin for SARS-CoV-2 via inhibitory effects on 3CLpro.
Mody et al., 1/20/2021, peer-reviewed, 9 authors.
Please send us corrections, updates, or comments. Vaccines and treatments are both extremely valuable and complementary;
multiple approaches are required to cover all people and all existing and
future variants. We do not provide medical advice. Before taking any
medication, consult a qualified physician who can provide personalized advice
and details of risks and benefits based on your medical history and situation.
Treatment protocols for physicians are available from the FLCCC.