Rezk, 320 patient ivermectin late treatment study: 56% lower progression [p=0.06], 33% improved recovery [p=0.27], and 27% faster viral clearance [p=0.01] https://c19p.org/rezk
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miRNA-223-3p, miRNA- 2909 and Cytokines Expression in COVID-19 Patients Treated with Ivermectin
et al., Zagazig University Medical Journal, doi:10.21608/zumj.2021.92746.2329
Prospective 320 hospitalized moderate COVID-19+ patients in Egypt, 160 treated with ivermectin, showing lower mortality, improved recovery, and decreased cytokine expression with treatment. All patients were treated with HCQ. 7890/26-8-2020.
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risk of death, 80.0% lower, RR 0.20, p = 0.50, treatment 0 of 160 (0.0%), control 2 of 160 (1.2%), NNT 80, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm).
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risk of progression, 55.6% lower, RR 0.44, p = 0.06, treatment 8 of 160 (5.0%), control 18 of 160 (11.2%), NNT 16, 2 weeks, including deaths.
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risk of no recovery, 33.4% lower, RR 0.67, p = 0.27, treatment 14 of 145 (9.7%), control 20 of 138 (14.5%), NNT 21, 4 weeks, more patients were lost to followup in the control group.
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time to viral-, 27.3% lower, relative time 0.73, p = 0.01, treatment 160, control 160.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Rezk et al., 10/30/2021, prospective, Egypt, Africa, peer-reviewed, 4 authors, dosage 36mg days 1, 3, 6.
Contact:
nonnarezk@yahoo.com.
Late treatment
is less effective
is less effective
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