Ghauri, 90 patient ivermectin early treatment study: 92% improved recovery [p=0.04] https://c19p.org/ghauri
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Ivermectin Use Associated with Reduced Duration of Covid-19 Febrile Illness in a Community Setting
et al., International Journal of Clinical Studies & Medical Case Reports, doi:10.46998/IJCMCR.2021.13.000320 (preprint 12/15/2020)
Retrospective 95 outpatients in Pakistan with strong clinical suspicion of COVID-19 (testing was not widely available), with 40 patients treated with ivermectin, showing significantly shorter duration of febrile illness with treatment. Most patients also received HCQ, AZ, zinc, and aspirin. Authors note that there was a treatment delay-response relationship.
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risk of fever, 92.2% lower, RR 0.08, p = 0.04, treatment 0 of 37 (0.0%), control 7 of 53 (13.2%), NNT 7.6, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm), day 14.
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risk of fever, 86.4% lower, RR 0.14, p < 0.001, treatment 2 of 37 (5.4%), control 21 of 53 (39.6%), NNT 2.9, day 10.
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risk of fever, 55.7% lower, RR 0.44, p < 0.001, treatment 13 of 37 (35.1%), control 42 of 53 (79.2%), NNT 2.3, day 7.
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risk of fever, 42.2% lower, RR 0.58, p < 0.001, treatment 21 of 37 (56.8%), control 52 of 53 (98.1%), NNT 2.4, day 5.
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| Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates |
Ghauri et al., 12/15/2020, retrospective, Pakistan, South Asia, peer-reviewed, 6 authors, dosage 12mg days 1-6.
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